COMBINED CAPABILITIES
Researchers and organizations developing peptide therapeutics or diagnostics now have a single point of contact to utilize the newly combined products and services of the Mimotopes-Genzyme Pharmaceuticals Global Alliance:

• Peptide libraries for screening applications
  Intelligently designed libraries of unpurified custom peptides are frequently the fastest, most accurate way to answer questions about a vaccine, diagnostic or drug development project. By incorporating flexibility in their design and synthesis, Mimotopes' PepSets provide the ideal screening solution for a wide range of applications in immunology and drug discovery.

• Custom, modified, and labelled peptides for
  Research and Development
  Once the correct sequences for your studies have been ascertained, Mimotopes can synthesize them quickly and precisely using whatever combination of labelling or synthesis options as may be required.
  Custom peptides from Mimotopes are created in modern, automated synthesizers using mild Fmoc chemistry and advanced solid-phase techniques under the strictest quality procedures.

• Immunoassay based products and services
  Mimotopes' antipeptide antisera services create antibodies, including antiphosphopeptide antibodies, for use in a variety of immunoassays. Affinity purification, conjugated peptides, "MAP" peptides with a range of peptide purities are all available.
  Mimotopes can help with the design and choice of peptide antigens and offers a range of carriers for conjugation. Our polyclonal antibody production services are availble in a variety of species.
  

• Design and discovery of peptide based
  drug candidates
  The critical residues in pharmacologically active peptides such as neurotransmitters, hormones or chemokines can be rapidly located and subsequently analoged to obtain more potent leads and peptidomimetics.

• Analytical development and validation
  Genzyme Pharmaceuticals' state-of-the-art equipment ideal for feasibility studies, seamless process development from lab-scale to production-scale, analytical development, and validation throughout.
  Expertise in developing scalable manufacturing processes utilizing both solution and solid phase methodologies for peptide synthesis proven by a successful track record of projects reaching full-scale manufacture.

• Manufacture of peptide APIs in a cGMP facility
  Clinical or commercial manufacture of your active pharmaceutical ingredient (API) at Genzyme Pharmaceuticals' Swiss site, which has been successfully inspected by the US FDA, numerous customers, Corporate Compliance and holds a current GMP certificate issued by the Swissmedic.
  In-house development and multi-ton production of amino acid derivatives (AADs) and building blocks for non-natural AAD as well as key intermediates such as pseudoproline dipeptides, ensures cost-effective peptide API manufacture and the best possible control of the supply chain and regulatory requirements.
  View Custom Manufacturing brochure

• Quality assurance and regulatory filing support
  Genzyme Pharmaceuticals' stringent on-site quality management systems with resources worldwide provide reliable analytical testing, quality assurance and regulatory support that continually meets current registration requirements including DMF preparation and filing in various markets such as USA, Canada, EU & Japan.

• Tools for delivering oligonucleotide-based therapeutics
  Oligonucleotide-based therapeutics are one of the most promising approaches in disease treatment today, however the delivery of RNA and DNA derivatives into the cells of the target organ presents substantial challenges. Genzyme Pharmaceuticals provides value-added solutions for delivering such actives using a unique combination of products, services, technologies, and strategic relationships.
  View Oligo Delivery Brochure